Polycystic ovary syndrome

Learn More About Polycystic Ovary Syndrome (PCOS)

What Is Polycystic Ovary Syndrome?

Polycystic Ovary Syndrome (PCOS) is a common condition affecting approximately 5–18% of women and is the most common cause of irregular menstruation and amenorrhea. Multiple small follicles develop simultaneously in the ovaries, but none of them mature properly or ovulate, which can lead to irregular menstruation, hirsutism, obesity, and infertility.

A common endocrine disorder affecting approximately 5–10% of women of reproductive age!

If you have been diagnosed with Polycystic Ovary Syndrome, it is important to receive appropriate medical evaluation and treatment.

Multiple small follicles develop simultaneously, but none of them mature properly or ovulate, which can lead to irregular menstruation, hirsutism, obesity, and infertility.

A Common Endocrine Disorder Affecting Approximately 5–10% of Women of Reproductive Age

If you have been diagnosed with Polycystic Ovary Syndrome, it is important to receive appropriate medical evaluation and treatment. If amenorrhea associated with Polycystic Ovary Syndrome is left untreated, the risk of endometrial hyperplasia and endometrial cancer may increase. PCOS is also strongly associated with obesity, diabetes, and cardiovascular disease, and may increase the risk of metabolic syndrome. Therefore, regular monitoring and management are important.

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Causes

During each menstrual cycle, women typically develop one dominant follicle, which grows to approximately 2 cm before ovulation. If pregnancy does not occur, menstruation begins about two weeks later. In women with Polycystic Ovary Syndrome, 12 or more small follicles measuring 2–9 mm are generally observed in each ovary.

Several factors have been suggested as potential causes, including hormonal imbalances in the hypothalamic–pituitary–ovarian axis, insulin resistance, and excessive secretion of male hormones. However, the exact cause has not yet been clearly established, and research is ongoing.

Symptoms

Symptoms Associated with Ovulatory Disorders

Amenorrhea, uterine bleeding, irregular menstruation, and infertility.

Symptoms Associated with Excess Androgens

Hirsutism, acne, and hair loss.

Symptoms Associated with Metabolic Disorders

Type 2 diabetes, dyslipidemia, hypertension, endocrine and metabolic disorders, and obesity.

Treatment goals

Treatment is tailored to each patient’s symptoms and individual goals, with the following as the ultimate objectives:

  • Treatment of pelvic infections and tumors, when present
  • Protection of the endometrium from continuous estrogen stimulation
    (Prevention of endometrial hyperplasia and endometrial cancer)
  • Reduction of androgen production and blood levels
  • Reduction of the risk of cardiovascular disease and type 2 diabetes
    (Minimizing the effects of hyperinsulinemia)
  • Ovulation induction to achieve pregnancy